Everyone Needs Niacinamide. Here Are The Best Niacinamide Serums for Healthy Skin

Brand courtesy / Paula's Choice
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Is your skin craving hydration? Brightness? Protection? The best niacinamide serums we rounded up for you will give you just that and then some more. As an all-rounder and safe-for-all compound, niacinamide is more popular than ever, and for fair reasons. It’s one of the most stable and versatile ingredients in the skincare world that works for all skin types (sensitive-included) and pairs well with most actives, including retinol, vitamin C and even alpha-hydroxy acids. Yet, the beauty of niacinamide is that it addresses almost any possible skin concern, so whatever your goal — be it clogged pores, dehydration, a weakened barrier, oxidative stress, or uneven tone — you’ll definitely enjoy all the benefits of a niacinamide-infused serum.

How niacinamide works?

When it penetrates the epidermis, niacinamide helps build proteins that support skin structure, meaning it keeps your complexion firm and bouncy. Besides, using a niacinamide serum boosts the antioxidant defense, strengthens the protective barrier, brightens dark patches, shrinks pores look, enhances collagen and ceramide synthesis, and prevents moisture loss. And if it wasn’t enough, niacinamide tackles acne, too, thanks to its antibacterial and anti-inflammatory effects and also because it balances oil production (as it’s hydrating). Yep, it does quite a lot.

How to use niacinamide serums

For the best results, use your niacinamide serum every morning, and evening, on cleansed (and toned) complexion. Follow up with moisturizer and sunscreen (at AM).

The best niacinamide serums

We picked the best serums infused with niacinamide that target every skin concern out there. And so that your skin absorbs even more benefits, these serums are also spiked with nourishing, hydrating and restorative ingredients — the perfect addition to your skincare routine.

Allies Of Skin Prebiotics & Niacinamide Pore Refining Booster
Best overall

1. Allies Of Skin Prebiotics & Niacinamide Pore Refining Booster

Allies Of Skin made one of the best niacinamide serums with 10% strength, to which they added prebiotics and probiotics to reinforce the skin and fortify the barrier. The formula works a treat for refining pores’ look, preventing sensitivity, and reducing sun damage and dark spots over time. Cica extract, tocopherol, resveratrol, glutathione, and CoQ10 guard against free radicals, offsetting oxidative stress and preventing early aging signs.

PCA Skin Vitamin B3 Brightening Serum
Best for uneven skin tone

2. PCA Skin Vitamin B3 Brightening Serum

This serum is basically your dark spot’s worst nightmare. Besides 6% niacinamide, it’s got mulberry, green tea, and oligopeptide to brighten, plus plankton extract, which is also great for evening skin tone. They work synergistically to fade existing discoloration and prevent new spots from forming while also reinforcing the protective barrier. I’m pointing out that this product is fragrance-free, hence a great pick for sensitive skin.

La Roche-Posay Pure Retinol Face Serum 
Best for wrinkles

3. La Roche-Posay Retinol B3 Serum

To tackle aging signs, La Roche Posay Retinol B3 Serum fusions niacinamide, along with hyaluronic acid, gradual-release retinol, adenosine, and citric acid, each having its role in minimizing fine lines, wrinkles, and dark spots look. The lightweight formula absorbs in no time, without ever feeling sticky or tacky, plus it’s non-comedogenic, so it won’t clog your pores.

Glow Recipe Watermelon Glow Niacinamide Dew Drops
Editor’s choice

4. Glow Recipe Watermelon Glow Niacinamide Dew Drops

When a product gets five stars out of 5, you know it lives up to the hype. We consider it one of the best niacinamide serums because, in addition to the high amount of niacinamide, it loads sodium hyaluronate and watermelon extract, both great at hydrating and plumping the look of fine lines. It works great for all skin types and has a lightweight gel-like texture that absorbs in the blink of an eye, leaving a glossy finish.

Paula's Choice Niacinamide Concentrated Serum
Highest niacinamide concentration

5. Paula’s Choice 20% Niacinamide Serum

This advanced 20% niacinamide serum targets clogged pores, bumps, and discolorations, making your skin look brand new in as little as two weeks, per the brand claims. Plus, due to vitamin C and licorice root extract, Paula’s Choice Niacinamide Serum brightens, while the EGCG and green tea extracts prevent further dark spots by neutralizing free radicals. All, whilst glucosamine (hyaluronic acid-booster) supports hydration, plumping fine lines and wrinkles. The thick texture leaves skin feeling intensely hydrated and bouncy.

Youth To The People Retinal + Niacinamide Youth Serum
Best natural

6. Youth To The People Retinal + Niacinamide Youth Serum

This is the best anti-aging niacinamide serum with a natural formula that skips alcohol and fragrance. In addition to 5% niacinamide, the serum contains 0.15% retinol to gently resurface and diminish dark spots. Other ingredients worth mentioning are ceramides, squalane, cholesterol, and phytosphingosine — known for softening fine lines and trapping moisture into the skin while reinforcing the barrier to prevent further moisture loss. Yes, please.

The Ordinary Niacinamide Treatment for Acne
Best for blemishes

7. The Ordinary Niacinamide and Zinc

A dream for oily and acne-prone skin, this serum reduces acne-causing bacteria and minimizes pores’ look by regulating sebum production for real. It features a high amount of two of the most effective blemish-battling ingredients, aka 10% niacinamide and 1% zinc. The shot of zinc also helps repair damage and encourages collagen synthesis — which can be great for post-acne marks.

Dennis Stress Rescue Super Serum
Best for anti-stress

8. Dr. Dennis Gross Stress Rescue Super Serum

This serum is not only supercharged with niacinamide, but it takes care of your skin with squalane, caffeine, lactic acid, vitamin C, and a blend of botanical extracts meant to nourish, protect and strengthen. With a silky-smooth weightless texture, the serum sinks into the skin, where it reduces stress, eases redness, and banishes dullness while improving skin texture on all fronts. It works like a charm for all skin types, including breakout-prone and easily reactive.

I DEW CARE Purifying Face Serum with Niacinamide
Best K-Beauty

9. I Dew Care Juicy Kitten

This is a supercharged serum made with blemish-prone skin in mind, with a blend of niacinamide, zinc, kale, spirulina chlorella, plus a purifying complex. They all work synergistically to speed up pimple healing, balance sebum to prevent further breakouts, and soothe the complexion. One thing you should be aware of: it contains BHA, which makes the skin photosensitive, so you’d better apply it at night and always use sunscreen during the day.

Bliss Glow & Hydrate Day Serum
Best for dryness

10. Bliss Glow & Hydrate Day Serum

If your skin is dehydrated, reach for Bliss Glow & Hydrate Day Serum. In addition to being super rich in niacinamide, it packs humectants that pull moisture into the skin, including glycerin, aloe vera juice, and sodium hyaluronate. On top of that, the serum packs antioxidants to shield against oxidative stress and licorice extract to enhance brightness and radiance.

Cos De BAHA Niacinamide 10% Serum
Best wallet-friendly

12. Cos De Baha Niacinamide Serum

Cos De Baha Niacinamide Serum stands out as the best niacinamide serum under $10. It’s powered by 10% niacinamide and 1% zinc to address breakouts, blemishes, red marks, and irritated skin. There’s also hyaluronic acid to hydrate and plump the skin, making it appear bouncy and dewy. Plus, 78% of ingredients are from organic sources — good news for clean skincare lovers.

Who wrote this?
Ana Vasilescu
Ana Vasilescu
Ana Vasilescu is the founder and editor-in-chief of Women's Concepts. She has over 5 years of experience working in the beauty editorial industry and dermatological research and was an acne sufferer for over a decade. Ana is now an IAO and CPD-accredited skincare consultant keen to teach others about the importance of a consistent routine. She covers a wide range of topics in skincare—from buzzy ingredients to anti-aging and acne advice. She holds a BA in Sociology and Political Sciences from the National School of Political and Administrative Studies. Find her on LinkedIn or Instagram.
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