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Could Resveratrol and Retinol Used Together Be A Game-Changer?

Retinol with resveratrol is a winning duo.
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How satisfying to write about two of my absolute favorite skincare actives in one post, aka resveratrol vs. retinol. I love retinol serums as much as I do resveratrol, either in a glass or in skincare. Even if I’ve always taken a simple approach to my beauty regimen, I constantly keep these two heroes nearby. Separately, they are indeed two powerhouses, great for all skin types, but can you use resveratrol with retinol?

Resveratrol vs. retinol

Resveratrol is a powerful antioxidant needed to stay shielded so that free radicals don’t wreak havoc on the skin. But its strengths don’t stop here. Resveratrol improves cellular function, calms skin, soothes inflammation, brightens and hydrates. How could you not love it? On top of everything, resveratrol has small molecules that allow it to penetrate the skin, going deep into the tissue layers where it does its magic. It’s the fitting addition to your skin protection arsenal.

On the other hand, retinol is a vitamin A derivative that increases cell turnover, helping prevent wrinkles and diminish dark spots. Besides, its tiny molecules go beneath the epidermis where it stimulates collagen production. The result? Plump, smooth, clear, and wrinkle-free skin. The right way to target skin repair.  

Can you use resveratrol with retinol?

Yes, you can use resveratrol with retinol, making your skin seal myriad benefits of protection and repair. As the skincare loyal that you are, you know during the day, the skin needs antioxidants for prevention and, at night, repairing ingredients. So it makes total sense to say use resveratrol in your AM routine and leave retinol for the night. But resveratrol isn’t the best ingredient to use in the morning since it’s easily deactivated by sunlight. So, the right way to use resveratrol with retinol together is in your nightly skincare regimen.

Pairing resveratrol with retinol helps diminish the potentially irritating effects since resveratrol has anti-inflammatory benefits that aid in minimizing redness and peeling associated with retinol use. This is great news for those with easily reactive skin. David McDaniel, M.D., a dermatologist in Virginia Beach, Virginia, specializing in antioxidants and anti-aging medicine, said via Vogue, “We can combine fairly potent retinoids with these antioxidants (resveratrol) for enhanced anti-aging benefits, and also avoid most of the irritation typical of vitamin A creams.”

The verdict

All in all, if you want to use resveratrol with retinol, do it at night. It’s a powerful skincare cocktail that’ll make your skin love you back — and it does all the work while you sleep. Finally, our skincare dictionary and ingredients cheat list are great places to keep an eye on all skincare ingredients and learn how you can mix them for dramatic results.

Who wrote this?
Ana Vasilescu
Ana Vasilescu
Ana is a sociologist and feminist with a shared passion for literature, psychology, and skincare, the combo that made her determined to start Women's Concepts. With over five years of experience in dermatological research, she has now become a certified skincare consultant keen to convince others of the importance of a diligent routine. Her close relationships with dermatologists around the globe, along with years of researching, analyzing studies, and hand-testing products on a daily basis, made Ana one of the best persons you can get advice from.
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Women's Concepts relies on the latest scientific research to provide accurate, complete, and fact-based information in skincare, on which we're willing to stake our reputation. Our team includes skincare experts who are highly regarded in their fields and committed to upholding the best standards of research. We spend quality time vetting every single product we recommend and double-checking all the facts shared on Women's Concepts. We always stand on the side of inclusivity, and our mission is to help everyone fix their skin issues as they arise and leverage the products they buy to achieve their goals. You can view our expert review board and everything about our editorial guidelines here.
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